MOTYS™  »  Preclinical  »  Clinical  »  Pipeline

Clinical

A single MOTYS™ injection provides unparalleled, durable improvements in pain and function.

Large clinical database (n<350) provides clear
direction for successful Phase 3 clinical study execution

IND Phase 1 safety study
(n=20; 12-month follow up)

  • No safety findings, no immunological reactions
  • Potent and durable effect on symptom relief reported up to 12 months

Open-label RWE study
(n=140; 12-month follow up)

  • After 12 months, 70% still patients experience benefits from a single injection of MOTYS™

Phase 2b RCT
(n=215; 6-month follow up, placebo controlled)

  • 70% improvement on pain and mobility scores at 6 months
  • Informed the design of a risk mitigated Phase 3 study

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