Preclinical
In preclinical head-to-head comparisons,
MOTYS™ was proven superior to HA’s and steroids
Effect on pain and cartilage protection:
Potential for disease modification
In a rat OA model, MOTYS™ provided superior and more durable pain relief compared to HA or steroid.
MOTYS™ also provided superior effects on scores of cartilage protection.
Remarkably consistent, disease relevant biofactors
>300 regulatory proteins detected in MOTYS™ contribute to its biologic MoA
IL-1Ra
Anti-inflammatory
Reduction of pain and swelling
TIMP-3
Anti-catabolic
Mitigation of cartilage degeneration
bFGF
Pro-anabolic
New tissue formation through cell recruitment, differentiation, and/or proliferation
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